AOD-9604 (HGH Fragment 176–191) is a synthetic peptide corresponding to amino acids 176–191 of human growth hormone. It selectively activates beta-3 adrenergic receptors in adipose tissue, stimulating lipolysis without the hyperglycemic or mitogenic effects of full-length GH. Supplied as ≥99% pure lyophilized powder for in vitro and preclinical research.
Research Overview
- Selective beta-3 AR-mediated lipolysis in adipose tissue without altering blood glucose (Heffernan et al., 2001)
- Inhibition of lipogenesis from dietary carbohydrates and fat in animal models (Ng & Waters, 2004)
- Equivalent lipolytic activity to full-length GH at significantly lower doses in preclinical studies
- No observed impact on IGF-1 levels, insulin sensitivity, or cartilage growth in research models
- Favorable safety profile in Phase I/II human trials conducted by Metabolic Pharmaceuticals (Australia)
Biochemical Properties
- Sequence: Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe
- Molecular Weight: ~1,815 Da
- Half-Life: Minutes (plasma); subcutaneous administration extends bioavailability
- Form: Lyophilized powder, ≥99% purity (HPLC-verified)
- CAS Number: 221231-10-3
Purchase AOD-9604 for Research
Studien Peptide supplies AOD-9604 (HGH Fragment 176–191) as 10 mg lyophilized vials at ≥99% purity for licensed research institutions and investigators.
Shipping & Storage
AOD-9604 ships via cold-chain transport. Lyophilized peptides are temperature-controlled throughout shipping and arrive with a Certificate of Analysis. Store at 2–8 °C upon receipt.